Psychiatry in Action lab
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Psychiatry in Action lab

Welcome to the Psychiatry in Action lab

Lead by Dr Noham Wolpe, a Clinical psychiatrist and researcher

Our broad interest is in understanding the mechanisms of mental health factors, such as motivation and mood.

Mental Health Factors
Core focus
Computational + Clinical
Approach
Translational Impact
Goal
PsyAct lab group photo during a lab outing

Featured work

Emotion recognition positivity-bias figure
In the media

Age-related positivity bias in emotion recognition

Our latest study on age-related on aged related positivity bias in emotional recognition has received coverage from major outlets in the UK and Israel. This work reveals a link between the age-related positivity bias in emotion recognition and cognitive decline, hightlighting associated structural and functional brain differences - a connection that may serve as a potential marker for neurodegeneration.

European Neuropsychopharmacology cover image
Publication

Rethinking the assessment of negative symptoms

New research reveals schizophrenia's negative symptoms fall into two distinct categories: emotional expression and motivation deficits. While standard clinical tools effectively measure emotional expression, they inadequately capture motivation problems—critical for patient outcomes. This discovery may explain why many treatments have failed and highlights the need for more precise assessment methods in both research and clinical practice.

Recent research visualization image
Publication

Behavioral and brain differences in the processing of negative emotion in previously depressed individuals

Jakub’s paper was published in Emotion. We investigated the cognitive mechanisms behind attentional negativity bias in depression, linking slower processing of angry faces to increased activity in the insula, inferior frontal gyrus, and parietal cortex. The findings suggest this bias may persist beyond depression.

Talks

What is mental effort?

Mental effort is widely used but poorly defined. Here's a talk I gave at CRCNS that summarises what we think about mental effort. The paper is here or in our publications page.

Mental effort talk